{"links":{"self":"https://petition.parliament.uk/petitions/732380.json"},"data":{"type":"petition","id":732380,"attributes":{"action":"Review Maternal Vaccine-Induced IL-6 Responses on Foetal Brain Development","background":"We call for an independent assessment of vaccination policies for use during pregnancy, focusing on vaccines that induce increases in IL-6. ","additional_details":"With no safe maternal IL-6 threshold established, this assessment should be precautionary and review guidance to minimise vaccine-induced IL-6 elevation during pregnancy.\r\n\r\nVaccinations activate innate immune (DAMP) pathways that produce IL-6, a cytokine shown to influence foetal brain development. Studies in animals and humans demonstrate that elevated maternal IL-6 levels during pregnancy, not infection per se, can be associated with adverse neurodevelopmental changes in offspring. Maternal vaccination policies should fully account for these known biological effects, reflect the latest scientific evidence, and adopt a precautionary approach to protect foetal health.","committee_note":"","state":"open","signature_count":17,"closing_date":"2026-08-09","created_at":"2025-07-04T12:10:00.753Z","updated_at":"2026-08-05T13:52:30.000Z","rejected_at":null,"opened_at":"2026-02-09T09:52:44.528Z","closed_at":null,"moderation_threshold_reached_at":"2025-07-05T14:50:20.000Z","response_threshold_reached_at":null,"government_response_at":null,"debate_threshold_reached_at":null,"debate_scheduled_on":null,"scheduled_debate_date":null,"debate_outcome_at":null,"creator_name":"Len duggan","rejection":null,"government_response":null,"debate":null,"departments":[{"acronym":"DHSC","name":"Department of Health and Social Care","url":"https://www.gov.uk/government/organisations/department-of-health-and-social-care"}],"topics":[],"signatures_by_country":[{"name":"United Kingdom","code":"GB","signature_count":17}],"signatures_by_constituency":[{"name":"Brighton Pavilion","ons_code":"E14001130","mp":"Siân Berry MP","signature_count":3},{"name":"Christchurch","ons_code":"E14001171","mp":"Sir Christopher Chope MP","signature_count":1},{"name":"Ealing Southall","ons_code":"E14001209","mp":"Deirdre Costigan MP","signature_count":1},{"name":"East Wiltshire","ons_code":"E14001217","mp":"Danny Kruger MP","signature_count":1},{"name":"East Worthing and Shoreham","ons_code":"E14001218","mp":"Tom Rutland MP","signature_count":1},{"name":"Harrogate and Knaresborough","ons_code":"E14001269","mp":"Tom Gordon MP","signature_count":1},{"name":"Hove and Portslade","ons_code":"E14001296","mp":"Rt Hon Peter Kyle MP","signature_count":2},{"name":"Lichfield","ons_code":"E14001335","mp":"Dave Robertson MP","signature_count":1},{"name":"Newton Abbot","ons_code":"E14001381","mp":"Martin Wrigley MP","signature_count":1},{"name":"Rochester and Strood","ons_code":"E14001447","mp":"Lauren Edwards MP","signature_count":1},{"name":"Stoke-on-Trent Central","ons_code":"E14001520","mp":"Gareth Snell MP","signature_count":1},{"name":"Torbay","ons_code":"E14001551","mp":"Steve Darling MP","signature_count":1},{"name":"Worthing West","ons_code":"E14001599","mp":"Dr Beccy Cooper MP","signature_count":1},{"name":"Cardiff South and Penarth","ons_code":"W07000091","mp":"Stephen Doughty MP","signature_count":1}],"signatures_by_region":[{"name":"Yorkshire and The Humber","ons_code":"D","signature_count":1},{"name":"West Midlands","ons_code":"F","signature_count":2},{"name":"London","ons_code":"H","signature_count":1},{"name":"South East","ons_code":"J","signature_count":8},{"name":"South West","ons_code":"K","signature_count":4},{"name":"Wales","ons_code":"L","signature_count":1}],"other_parliamentary_business":[]}}}